MSI CG480-S5063 Air-Cooled NVIDIA MGX 4U GPU Server
The MSI CG480-S5063 is a 4U Intel Xeon-based NVIDIA MGX server.
On the front, we get most of the panel dedicated to airflow, but we also get plenty of drive bays for local storage.
By using E1.S SSDs, MSI is able to fit plenty of storage (20x E1.S SSDs) into the server without restricting as much airflow as using U.2 SSDs.
On the cooling front, we see a common design with hot-swappable fans for the bottom section of the chassis.
The internal fans are split between the bottom (front) and top (midplane) fans to cool different parts of the system. We can also see that this PCIe daughterboard is using PCIe switches, which is also why we get so much storage capacity.
These servers can handle the NVIDIA RTX Pro 6000 Blackwell, as well as the new NVIDIA RTX Pro 4500 Blackwell Edition cards.
For those who want a similar form factor but a very different implementation, we saw another option at GTC 2026.
MSI CG481-S6053 4U Air-Cooled GPU Server
The MSI CG481-S6053 is a similar design from the front with storage on the top 2U and fans on the bottom 2U of the server.
One major difference is that instead of 20x E1.S SSDs, we get 8x U.2 SSDs. That may sound like a major downgrade, but also consider that with 245TB/ 256TB class U.2 drives, this system can handle roughly 2PB of local storage.
The bottom front hot swap fan design is very similar.
Also, we get the top 2U of fans as an internal midplane fan partition.
Here, the system has eight NVIDIA RTX Pro 6000 Blackwell Server Edition GPUs. It is also an NVIDIA ConnectX-8 PCIe switch PCB platform, with four NVIDIA ConnectX-8 controllers on the board, eliminating the need for PCIe switches and additional PCIe slots for NICs. Each GPU has its own 400Gbps link.
This system also supports other GPUs like the NVIDIA H200 NVL and NVIDIA RTX Pro 4500 Blackwell Server Edition and is powered by the AMD EPYC 9005 “Turin” series.
Next, let us get to the GB10.
